There are so many options for road trips in northern Greece. Apart from the road trip from Thessaloniki outlined here, the following are great bases from which to explore, with mountains, local traditions, fantastic food and nature activities.
Kavala: A city that blends east and west, with sandy beaches and beautiful day-trips to enjoy in the region, including Thassos (Greece’s northernmost island).
Kastoria: A lakeside jewel with fascinating neighbourhoods and a springboard to treasures such as the Prespes Lakes, Nymfaio, Grevena and the North Pindos Mountains.
Ioannina: Another lakeside treasure brimming with history and a stepping stone to the Zagorochoria mountain villages and the Pindos Mountains.
Halkidiki: The entire region has road-trip potential, from the beaches of Kassandra and Sithonia, to the mountain villages and wineries of central Halkidiki. To the east lies the Mt Athos peninsula.